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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Etanercept

4

I.y Progression, acceleration or exacerbation of preexisting ILD/fibrosis

1
Last update : 30/05/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
TNF-alpha antagonists / inhibitors
5

Publications

Eternacept for the treatment of patients with rheumatoid arthritis and concurrent interstitial lung disease.
Journal of clinical pharmacy and therapeutics 2012 Feb;37;117-21 2012 Feb
Acute exacerbation of preexisting interstitial lung disease after administration of etanercept for rheumatoid arthritis.
The Journal of rheumatology 2007 May;34;1151-4 2007 May

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