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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Etanercept

4

V.d Pleural/pericardial effusion, ANA positive (DI lupus)

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
TNF-alpha antagonists / inhibitors
5

Publications

Registries in rheumatoid arthritis and autoimmune diseases: data from the French registries.
Rheumatology (Oxford, England) 2011 Jan;50;222-9 2011 Jan
Lupus-like syndrome attributable to anti-tumor necrosis factor alpha therapy in 14 patients during an 8-year period at Mayo Clinic.
Mayo Clinic proceedings 2009 Nov;84;979-84 2009 Nov
Etanercept-induced pleuropericardial lupus-like syndrome.
The European respiratory journal 2009 Apr;33;939-41 2009 Apr
[Development of systemic lupus erythematosus with focal proliferative lupus nephritis during anti-TNF-alpha therapy for psoriatic arthritis].
Medizinische Klinik (Munich, Germany : 1983) 2007 Oct 15;102;852-7 2007 Oct 15

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