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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Vaccination - Immunization

2

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

1
Last update : 20/02/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
BCG therapy (topical instillations in the urinary bladder)
5
Hepatitis B vaccination
1
Immune checkpoint inhibitors (ICI) - ICI combinatorial Rx
5
Influenza vaccine
2
Tetanus vaccination
1

Publications

Pediatric anaphylactic adverse events following immunization in Victoria, Australia from 2007 to 2013.
Vaccine 2015 Mar 24;33;1602-7 2015 Mar 24
Fatal anaphylactic shock; occurrence in identical twins following second injection of diphtheria toxoid and pertussis antigen.
Journal of the American Medical Association 1946 Jun 29;131;730-5 1946 Jun 29

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