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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Ergotamine

2

XII.k Constrictive pericarditis - Pericardial thickening

1
Last update : 10/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Bromocriptine
3
Cabergoline
3
Dihydroergocristine
1
Dihydroergocryptine
1
Dihydroergotamine
1
Ergonovine
1
Ergots, ergot alkaloids, ergolines
4
Methysergide
2
Nicergoline
1
Pergolide
3

Publications

Ergotamine-induced pleural and pericardial effusion successfully treated with colchicine.
Acta clinica Belgica 2013;68;113-5 2013
Pleural and pericardial fibrosis after ergotamine therapy.
Respiratory medicine 1994 Jul;88;480 1994 Jul
Pleural and pericardial fibrosis after ergotamine therapy.
Respiratory medicine 1994 Jan;88;67-9 1994 Jan
Fibrotic processes associated with long-term ergotamine therapy.
The New England journal of medicine 1984 Aug 30;311;601-2 1984 Aug 30

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