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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Radiopharmaceuticals

2

II.b ARDS - Acute lung injury

2
Last update : 03/12/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Radiation therapy, infusional (injected 131I or 90Y radioactivity)
2

Publications

Adverse reactions to radiopharmaceuticals in France: analysis of the national pharmacovigilance database.
The Annals of pharmacotherapy 2015 Jan;49;39-47 2015 Jan
¹³¹I-labeled lipiodol-induced interstitial pneumonia: a series of 15 cases.
Chest 2011 Jun;139;1463-1469 2011 Jun

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