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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Sibutramine

1

VI.b Pulmonary arterial hypertension

1
Last update : 14/07/2021
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Amphetamine (and -derivatives)
3
Herbals - Dietary botanical therapy - Health products/food - Plants
5

Publications

Giant pulmonary artery aneurysm caused by sibutramine-associated pulmonary arterial hypertension: First case in the literature.
Anatolian journal of cardiology 2021 Jul;25;512-514 2021 Jul

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