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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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T cell therapy

1

II.b ARDS - Acute lung injury

1
Last update : 30/11/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2.
Molecular therapy : the journal of the American Society of Gene Therapy 2010 Apr;18;843-51 2010 Apr

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