v2.2
Contact
News
Diagnosing DIRD
Browse
Available on AppStore
The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
Browse by »
Drugs
Patterns
Pembrolizumab
5
XII.s
Heart block (bundle branch- or AV-)
1
Last update :
23/10/2018
Search
Search
Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Atezolizumab
Immune checkpoint inhibitors (ICI) - ICI combinatorial Rx
Ipilimumab
Lambrolizumab
Nivolumab
PD-1/PD-L1-inhibitors or blocking agents/drugs
Publications
Pembrolizumab-Induced Mobitz Type 2 Second-Degree Atrioventricular Block.