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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Docetaxel

3

X.g Hypersensitivity reaction (may manifest with fever and/or skin, throat or airway involvement)

2
Last update : 07/01/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
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Remission of symptoms with removal of drug
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Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Paclitaxel
5

Publications

Docetaxel (Taxotere) in advanced malignant melanoma: a phase II study of the EORTC Early Clinical Trials Group.
European journal of cancer (Oxford, England : 1990) 1994;30A;1061-4 1994
Coping with toxicities of docetaxel (Taxotere).
Annals of oncology : official journal of the European Society for Medical Oncology 1993 Aug;4;610-1 1993 Aug

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