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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Clenbuterol
1
XI.d
Metabolic acidosis (incl. lactic acidosis/-gap). May cause hyperpnea/dyspnea
1
Last update :
14/11/2014
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
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Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
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Remission of symptoms with removal of drug
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Recurrence with rechallenge (rarely advisable)
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Causality assessment
More detailed checklist
See also under
Adulterants, contaminants, cutting agents
Heroin (inhaled, insufflated, snorted)
Heroin (intravenous)
Heroin (oral)
Publications
Palpitations, hypotension, hypokalemia, and hyperlactatemia. Putting the pieces together.