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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Trastuzumab emtansine (Ado-trastuzumab emtansine - TDM-1)

1

X.d Lupus - Lupus syndrome (see also Vd)

1
Last update : 25/11/2024
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Trastuzumab
5
Trastuzumab deruxtecan
4

Publications

Drug induced lupus associated with Trastuzumab emtansine in a patient with metastatic breast cancer.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 2025 Jan;31;168-171 2025 Jan

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