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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Adrenaline (epinephrine)

3

II.d Pulmonary edema, cardiogenic

1
Last update : 11/03/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Life-Threatening Accidental Intravenous Epinephrine Overdose in a 12-Year-Old Boy.
Pediatric emergency care 2019 Jun;35;e110-e112 2019 Jun
Adrenaline in anaphylaxis treatment. Balancing benefits and harms.
Expert opinion on drug safety 2016 Jun;15;741-6 2016 Jun
Accidental intravenous administration of 50 mg of racemic adrenaline in a 2-year-old boy.
European journal of anaesthesiology 1995 Mar;12;181-3 1995 Mar
Acute pulmonary edema after regional anesthesia with lidocaine and epinephrine in a patient with chronic renal failure.
Anesthesia and analgesia 1984 Mar;63;363-4 1984 Mar

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