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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Adrenaline (epinephrine)

3

II.a Pulmonary edema, noncardiogenic (NCPE)

2
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Adrenaline induced pulmonary oedema.
Journal of anaesthesiology, clinical pharmacology 2011 Jan;27;132-3 2011 Jan
Acute pulmonary edema after local infiltration of epinephrine during mastoidectomy: A case report.
Korean journal of anesthesiology 2009 Apr;56;462-465 2009 Apr
Lessons for management of anaphylaxis from a study of fatal reactions.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2000 Aug;30;1144-50 2000 Aug
Delayed-onset epinephrine-induced pulmonary edema.
Anesthesiology 1999 Oct;91;1169-70 1999 Oct
New developments in synthetic bone replacement materials.
Current opinion in dentistry 1992 Mar;2;97-103 1992 Mar
Adrenaline-induced pulmonary oedema and its treatment. A report of two cases.
British journal of anaesthesia 1971 Jul;43;709-12 1971 Jul

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