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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Adrenaline (epinephrine)

3

II.i Flash (fulminate) pulmonary edema

1
Last update : 01/10/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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Publications

Review of epinephrine solution use in 400 consecutive cases of burn reconstruction. Are infusion pumps safe?
Journal of burn care & research : official publication of the American Burn Association 2013;34;e305-7 2013
Lessons for management of anaphylaxis from a study of fatal reactions.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2000 Aug;30;1144-50 2000 Aug

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