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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Abacavir

2

II.a Pulmonary edema, noncardiogenic (NCPE)

1
Last update : 15/04/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Highly active antiretroviral therapy - HAART
3

Publications

Acute respiratory manifestations of the abacavir hypersensitivity reaction.
AIDS (London, England) 2006 Jan 09;20;301-2 2006 Jan 09

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