Pneumotox » Drug » Mephenidate (Methylphenidate)

Mephenidate (Methylphenidate)

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Trade name is Ritalin

Last update : 14/01/2017

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

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I.t Pneumoconiosis (silicosis, talcosis...)

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IV.n Obstructive airway dysfunction (see also IVc, XVx)

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V.f Pneumothorax

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VI.b Pulmonary arterial hypertension

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VI.g Foreign body pulmonary vasculopathy (Excipient lung disease)

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IX.k Trismus (lockjaw)

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X.m Vascultis (pulmonary, extrathoracic or systemic)-ANCA status unknown or negative)

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X.bb Foreign body (talc, cornstarch) retinopathy

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XI.b Chest pain (acute or subacute), lone or prominent

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XI.m Pulmonary emphysema - Lung cysts or bullae

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XII.g Coronary artery disease (acute) - Myocardial ischemia/infarction

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XV.b Path: Eosinophilic pneumonia (subacute or acute) (see also Ic)

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XV.q Path: Foreign body deposits/granulomatous reaction

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Diagnosing DIRD

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Drug and radiation history

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Drug singularity - Correct identification of the drug

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Consistent timing of exposure v. onset of symptoms

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Clinical, imaging, BAL, pathological pattern consistent with the specific drug

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Careful exlusion of another cause

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Remission of symptoms with removal of drug

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Recurrence with rechallenge (rarely advisable)

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Causality assessment

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